I was thinking that the industry has really branched out in it's quick evolution, in that time a whole lot of subjects and genres have been explored, i was wondering what a truly unique game would be like. So, any ideas?

Well You can look at the most recent Suda51 game: Killer is dead. That game is something special, Then there aresome that are way under radar like others which really expand into story while providing enjoyable gameplay. It's all a matter of who's who. Do you want to take risks and show what your vision really means, or join along the rest and ride the same horse until it dies. Just saying.